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Red Cell Immunohaematology

Reagents

Reagents are produced at the Liverpool Centre.

Contact Information

 
Quality Statement

All products are CE marked and comply with the standards laid down in the Guidelines for the Blood Transfusion Services in the U.K. (current edition) and are prepared to best standards of practice.

To maintain CE marking we work to ISO9000, Part 2 for production and design to meet the requirements of the EC in-vitro diagnostics directive with special reference to annex 2 which deals with ABO & Rh blood grouping and antibody detection.

Please note our CE Licensing arrangements are such that we only supply to The Irish Republic and the U.K.

Information leaflet about the products and services offered by NBS Reagents.

NBS Reagents Information Leaflet INF/DDR/RC/038/03 (PDF)

 
Reagents Price List

Reagents Product Inserts

Ordering of reagents

For information of these & other products contact one of the NBS Reagent laboratories

Reagents distribution schedule 2008-2009

Red Cell Reagents

Antibody detection and identification

Antiglobulin test

Serological controls and other products

 
Reagents Price List

A price list for NBS Reagents 2008 - 2009 can be found below:

NBS Reagents Portfolio 2008-09 (PDF)

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Reagents Product Inserts

Please find below the product name and document reference:

Reagent Red Cells

NBS Reagents and DiaMed GRU files
ABO control cells INF/DDR/RE/007/03
ABO control cells in CellStab INF/DDR/RE/011/03
IgG coated cells INF/DDR/RE/008/03
rr screening cells INF/DDR/RE/009/03
Screening cells INF/DDR/RE/022/02
Screening cells in CellStab INF/DDR/RE/015/03
Panel cells INF/DDR/RE/024/02
Panel cells in CellStab INF/DDR/RE/012/03
Whole blood controls INF/DDR/RE/014/03
Reagent red cells for the titration of red cell antibodies INF/DDR/RE/017/03
Papain Solution Product Insert INF/DDR/RE/035/01 (PDF)

Serological controls for in vitro diagnostic use only

AB serum INF/DDR/RE/010/04
Weak anti-D INF/DDR/RE/005/05
Weak anti-c INF/DDR/RE/002/06
Weak anti-Fya INF/DDR/RE/003/06
Weak anti-K INF/DDR/RE/004/06

Reagents for use in serological investigation

ZZAP INF/DDR/RE/006/04

Reagent Product Material Safety Data Sheets (MSDS)

Red cell reagents in Alsevers INF/DDR/RC/006/06 (PDF)
Red cell reagents in CellStab INF/DDR/RC/007/05 (PDF)
Red cell reagents in LISP INF/DDR/RE/001/03 (PDF)
Weak antisera for control use INF/DDR/RC/019/07 (PDF)
AB serum INF/DDR/RC/028/04 (PDF)
ZZAP INF/DDR/RC/029/04 (PDF)
Papain solution INF/DDR/RC/031/03 (PDF)
Whole blood controls INF/DDR/RC/059/02 (PDF)

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Ordering of reagents

Reagents can be ordered on a standing order basis which is renewed each year, or on an ad-hoc basis by telephone with written confirmation to one of the reagent departments.

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Red Cell Reagents

All cells have a four week expiry date and are CE marked.

ABO reverse grouping and Rh control cells.

10mL volumes of 3% A1,A2,B rr cells and OR1r in Alsevers
10mL volumes of 0.8%Arr and Brr cells in DiaMed CellStab

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Antibody detection and identification

2-cell screen* - consisting of OR1R1 and OR2R2 with homozygous expression of the S, s, Fya, Fyb, Jka and Jkb antigens and positive for K, P1, N, Lea and Leb.

3-cell screen* - consisting of OR1R1, OR2R2, and Orr with homozygous expression of the antigens as per the 2-cell screen.

Screening cells are supplied in Alsevers or DiaMed CellStab.

A range of antibody identification panels are available and are supplied as native or enzyme treated in preservative solution or in Diamed CellStab. Each panel is derived from a different set of donors to allow better identification of antibody mixtures.

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Antiglobulin test

IgG coated cells

For addition to apparent negative antiglobulin reactions to ensure that there has been no inhibition of the anti-IgG.Sensitised with anti-D to give a grade 2-3 positive reaction to help ensure that even partial inhibition is detected.

Supplied as 1 x 10 mL of 4% suspension

Weak IgG anti-D control

(approx. 0.1 iu/mL) for use as a positive control in antibody screening

Weak anti-c,anti-K and anti-Fya controls. Supplied as 1 x 10 mL volumes

Inert serum from group AB donors for use as a negative control

Supplied as 1 x 10 mL volume

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Serological controls and other products

Whole blood controls

A and B cells (one of which is Rh D positive and the other Rh D negative. One containing anti-D and the other anti-K. Supplied as a set of 2 x 5 mL volumes.

IPEx

Supplied 6 times a year this can be used for internal proficiency testing, staff training etc. Most exercises are accompanied by some CPD questions.

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For information on these and other products contact:

Liverpool 0151 552 7157
reagentscs@nbs.nhs.uk

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